G7528 Sigma-Aldrich


BioXtra, ≥99.5% (GC)

Synonym: Dextrose

  • CAS Number 50-99-7

  • Empirical Formula (Hill Notation) C6H12O6

  • Molecular Weight 180.16

  •  Beilstein/REAXYS Number 1724615

  •  EC Number 200-075-1

  •  MDL number MFCD00063774

  •  PubChem Substance ID 24895314

  •  NACRES NA.21



Related Categories Aerobic Glycolysis (the Warburg Effect), Biochemicals and Reagents, Cancer Metabolism, Cancer Research, Carbohydrates,
Quality Level   200
biological source   maize
product line   BioXtra
assay   ≥99.5% (GC)
form   powder
optical activity   [α]20/D +53±2°, 3 hr, c = 10 in H2O(lit.)
application(s)   gas chromatography (GC): suitable
impurities   Insoluble matter, passes filter test
ign. residue   ≤0.1% (as SO4)
loss   ≤0.1% loss on drying
mp   150-152 °C (lit.)
solubility   H2O: 1 M, clear, colorless
anion traces   chloride (Cl-): ≤0.005%
  sulfate (SO42-): ≤0.005%
cation traces   Al: ≤0.0005%
  As: ≤0.0001%
  Ba: ≤0.0005%
  Bi: ≤0.0005%
  Ca: ≤0.001%
  Cd: ≤0.0005%
  Co: ≤0.0005%
  Cr: ≤0.0005%
  Cu: ≤0.0005%
  Fe: ≤0.0005%
  K: ≤0.005%
  Li: ≤0.0005%
  Mg: ≤0.0005%
  Mn: ≤0.0005%
  Mo: ≤0.0005%
  Na: ≤0.005%
  Ni: ≤0.0005%
  Pb: ≤0.0005%
  Sr: ≤0.0005%
  Zn: ≤0.0005%
absorption   ≤0.02 at 260 in H2O at 1 M
  ≤0.03 at 280 in H2O at 1 M
storage temp.   room temp
SMILES string   OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
InChI   1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
Gene Information   human ... PYGM(5837)


General description

Glucose/dextrose is a carbohydrate compound or an aldohexose, present in humans. It is used as fuel by cells. Glucose consists of six carbon atoms and an aldehyde group. This monosaccharide can exist in an open-chain (acyclic) and ring (cyclic) form. It plays an important role in animal metabolism. Glucose, a major product of photosynthesis, participates in cellular respiration to generate adenosine triphosphate (ATP) and NADH (nicotinamide adenine dinucleotide).


D-(+)-Glucose has been used:
• as a component of Tris-glucose-EDTA (TGE) buffer for the preparation of bacterial DNA
• in the preparation of peptide dilution buffer (PDB)
• in the preparation of M17 broth medium
• in the preparation of phosphate-buffered saline (PBS) buffer, used in phosphate calcium transfection


1 kg in poly bottle

10 mg in glass bottle

250 g in poly bottle

5 kg in poly drum

Safety & Documentation

Safety Information

Personal Protective Equipment 
NONH for all modes of transport
WGK Germany 


Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Frequently Asked Questions

How does the storage temperature relate to shipping conditions?
The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment. See Shipping and Storage for more information.
Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
Is Product G7528, D-(+)-Glucose, the same as dextrose?
Yes, the D-(+) form of glucose is also known as dextrose.
Can solutions of Product G7528, D-(+)-Glucose, be autoclaved?
Yes, solutions can be autoclaved.
IsProduct G7528, D-(+)-Glucose, the alpha or the beta form of D-(+)-Glucose?
This product is a mixture of alpha and beta anomers, although it is primarily the alpha anomer.
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Protocols & Articles


Insulin Signaling and Energy Homeostasis

Glucose metabolism is regulated by the opposing actions of insulin and glucagon. Insulin is released from pancreatic ß cells in response to high blood glucose levels and regulates glucose metabolism ...
Linda Stephenson, Ph.D.
Biofiles v6 n4, 2011
Keywords: Apoptosis, Biological processes, Carboxylations, Catalog, Diabetes, Gene expression, Gluconeogenesis, Glycolysis, Hormones, Metabolism, Metabolites, Transcription, Transduction, Type

Peer-Reviewed Papers


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