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G8293 Sigma-Aldrich

Galanin (2-11) porcine, rat

≥97% (HPLC), lyophilized powder

  • Empirical Formula (Hill Notation) C54H81N13O14

  • Molecular Weight 1136.30

  •  MDL number MFCD05664726

  •  PubChem Substance ID 329799978

  •  NACRES NA.32

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Properties

Related Categories Approved Therapeutics/Drug Candidates, AstraZeneca, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   200
biological source   synthetic
assay   ≥97% (HPLC)
form   lyophilized powder
composition   Peptide content, ≥65%
storage temp.   −20°C
SMILES string   CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2c[nH]c3ccccc23)[C@@H](C)O)C(N)=O
InChI   1S/C54H81N13O14/c1-26(2)17-37(46(57)73)62-49(76)38(18-27(3)4)63-51(78)40(20-31-13-15-33(70)16-14-31)61-44(72)24-59-47(74)29(7)60-53(80)42(25-68)66-52(79)41(22-43(56)71)64-50(77)39(19-28(5)6)65-54(81)45(30(8)69)67-48(75)35(55)21-32-23-58-36-12-10-9-11-34(32)36/h9-16,23,26-30,35,37-42,45,58,68-70H,17-22,24-25,55H2,1-8H3,(H2,56,71)(H2,57,73)(H,59,74)(H,60,80)(H,61,72)(H,62,76)(H,63,78)(H,64,77)(H,65,81)(H,66,79)(H,67,75)/t29-,30+,35-,37-,38-,39-,40-,41-,42-,45-/m0/s1
InChI key   SUJPPMXJCZETOA-ZKEPBWIVSA-N
Gene Information   rat ... Gal(29141)

Description

Amino Acid Sequence

Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-NH2

General description

Galanin (2-11) is a galanin receptor type 2 agonist.

Packaging

500 μg in glass bottle

Biochem/physiol Actions

Studies in mice show that injection of galanin (2-11) has anticonvulsant activity in seizure affected animals with an intact DR (dorsal root)–hippocampal serotonergic profile, and has no effect in animals with absent 5-HT (hydroxytryptamine) profile.

Other Notes

Lyophilized from 0.1% TFA in H2O

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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