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G8769 Sigma-Aldrich

D-(+)-Glucose solution

45% in H2O, sterile-filtered, BioXtra, suitable for cell culture

  • CAS Number 50-99-7

  • Empirical Formula (Hill Notation) C6H12O6

  • Molecular Weight 180.16

  •  Beilstein/REAXYS Number 1281608

  •  EC Number 200-075-1

  •  MDL number MFCD00063774

  •  PubChem Substance ID 24895351

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Properties

Related Categories Cell Culture, Miscellaneous Reagents and Supplements, Reagents and Supplements More...
InChI Key   WQZGKKKJIJFFOK-DVKNGEFBSA-N
sterility   sterile-filtered
product line   BioXtra
form   solution
concentration   45% in H2O
impurities   endotoxin, tested
suitability   suitable for cell culture
Gene Information   human ... PYGM(5837)

Description

General description

Glucose is the energy currency essential for physiological processes in the living cells. It serves as a precursor for glycoproteins, glycolipids and glycosaminoglycans.

Application

D-(+)-Glucose solution has been used as a medium supplement:
• in Dulbecco′s Modified Eagle Medium (DMEM) for culturing Flp-In  293 cells
• in dissection medium for coronal slices from rat brain
• in neurobasal medium for culturing hippocampi cells

Biochem/physiol Actions

Glucose is a crucial component for the growth and maintenance of mammalian cells in in vitro conditions and is essential for productivity and quality. Its high metabolic turnover favors osteoclast differentiation. The levels of glucose modulate the migration and growth of tumor cells. HeLa cells display high mobility at low glucose levels.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1

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Cell Culture Guide
Protocols & Articles

Articles

Insulin Signaling and Energy Homeostasis

Glucose metabolism is regulated by the opposing actions of insulin and glucagon. Insulin is released from pancreatic ß cells in response to high blood glucose levels and regulates glucose metabolism ...
Linda Stephenson, Ph.D.
Biofiles v6 n4, 2011
Keywords: Apoptosis, Biological processes, Carboxylations, Catalog, Diabetes, Gene expression, Gluconeogenesis, Glycolysis, Hormones, Metabolism, Metabolites, Transcription, Transduction, Type

Related Content

Cell Culture Troubleshooting Guide

Cell culture has become one of the most fundamental techniques for modeling biological systems, and is of increasing importance in the biotechnology and pharmaceutical sectors as well as an essential...
Keywords: Antibiotics, Apoptosis, Cell attachment, Cell culture, Cryopreservation, Filtration, Growth factors, Pharmaceutical, Phase transitions

Peer-Reviewed Papers
15

References

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