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  • G9415 - Anti-GFRα-2 antibody produced in rabbit

G9415 Sigma

Anti-GFRα-2 antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym: Anti-GDNF receptor-β, Anti-GDNFR-β, Anti-NTNR-α, Anti-RETL2, Anti-TmR2, Anti-neurturin receptor-α



Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Kinase/Phosphatase Biology, Antibodies to Cytokines and Growth Factors,
species reactivity   mouse, human, rat
application(s)   western blot: 1-2 μg/mL using human HeLa cell extract
clone   polyclonal
antibody form   IgG fraction of antiserum
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... GFRA2(2675)
mouse ... Gfra2(14586)
rat ... Gfra2(25136)
biological source   rabbit
conjugate   unconjugated



synthetic peptide corresponding to amino acids 377-391 of human GFRα-2.

General description

GDNF family receptor α (GFR α) is a glycosylphos phatidylinositol (GPI)-anchored protein that belongs to GDNFR family. GFR α expresses mainly in nervous system. It behaves as a co-receptor to activate Ret and can facilitates the GDNF, NTN, PSP, and ART signaling. GDNF binds preferentially to GFR α-1, NTN to GFR α -2, ART to GFR α -3, and PSP to GFR α-4. Rabbit anti-GFRα-2 antibody reacts specifically with mouse, rat or human GFR α 2.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide


Anti-GFR α-2 antibody can be used in western blotting (1-2 μg/mL) using human HeLa cell extract.

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Safety & Documentation


Certificate of Analysis

Certificate of Origin

Safety Information

Symbol  GHS07  GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P305 + P351 + P338
RIDADR  NONH for all modes of transport
WGK Germany  1
Protocols & Articles


Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy


Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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