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  • G9419 - Anti-GABAA Receptor (β1 subunit), Cytosolic Loop antibody produced in rabbit

G9419 Sigma-Aldrich

Anti-GABAA Receptor (β1 subunit), Cytosolic Loop antibody produced in rabbit

~0.2 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

Synonym: Anti-γ-Aminobutyric Acid Type A Receptor (β1 subunit)



Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to GABA and Glycine Receptors, Antibodies to Ion Channels,
conjugate   unconjugated
clone   polyclonal
biological source   rabbit
application(s)   western blot: 1:1,000 using rat membrane fraction
species reactivity   rat
mol wt   antigen apparent mol wt 51-54 kDa
form   buffered aqueous glycerol solution
shipped in   wet ice
storage temp.   −20°C
antibody form   affinity isolated antibody
Quality Level   200
antibody product type   primary antibodies
usage   sufficient for 10 blots
concentration   ~0.2 mg/mL
UniProt accession no.   P15431
Gene Information   rat ... Gabrb1(25450)


General description

GABAA and GABAB receptors differ with regard to their ionic characteristics and pharmacological properties. The GABAA receptor is an ionotropic receptor that forms the GABA gated chloride channel and consists of several heterogeneous subunits with membrane recognition sites for benzodiazapenes. GABAA receptor is a ligand-gated chloride channel that is a multimeric subunit complex. So far, around 16 subunits have been identified. This gene encodes the β1 subunit, which maps to human chromosome 4p12. It is present in a cluster along with genes encoding α 4, α 2 and γ 1 subunits of the GABA A receptor.


fusion protein with the amino acid sequence representing the cytosolic loop of the rat GABAA receptor (β1 subunit)


Anti-GABAA Receptor (β1 subunit), Cytosolic Loop antibody produced in rabbit is suitable for western blotting at a working dilution of 1:1000 using rat membrane fraction.

Physical form

Solution in 10 mM HEPES, pH 7.5, 150 mM NaCl, 100 μg/mL BSA, and 50% glycerol


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biochem/physiol Actions

The inhibitory neurotransmitter GABA signals through two distinct types of pre- and postsynaptic receptors, GABAA and GABAB. Both GABA receptors can regulate depression of synaptic transmission and be involved in the inhibition controlling neuronal excitability. Disruption in this receptor is implicated in autism. Alterations in N-glycosylation of α1, β1, and β2 have been observed in schizophrenic patients.

Safety & Documentation

Safety Information

WGK Germany 


Certificate of Analysis (COA)

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Protocols & Articles


Antibody Basics

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Western Blot Protocol | Immunoblotting Protocol

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