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GW20080F Sigma-Aldrich

Anti-Haptoglobin antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Synonym: Anti-MGC111141

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Properties

Related Categories A to L, Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Immune Cell Signaling and Blood,
conjugate   unconjugated
clone   polyclonal
biological source   chicken
application(s)   indirect ELISA: suitable
  western blot: suitable
species reactivity   human, mouse, rat
form   buffered aqueous solution
shipped in   wet ice
storage temp.   −20°C
antibody form   affinity isolated antibody
Quality Level   200
antibody product type   primary antibodies
mfr. no.   Genway, 15-288-20080F
NCBI accession no.   NP_005134.1
UniProt accession no.   P00738
Gene Information   human ... HP(3240)

Description

Immunogen

Haptoglobin native protein.

Immunogen Sequence: GI # 4826762, sequence 1-406

Application

Anti-Haptoglobin antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biochem/physiol Actions

Haptoglobin (abbreviated as Hp) is the protein encoded by the HP gene in humans. It is an "acute phase" protein that has different functions displaying genetic polymorphism and has are 3 major phenotypes. Haptoglobin is capable of binding haemoglobin, there by preventing iron loss and renal damage. The complex of haptoglobin with haemoglobin is metabolized in the heptic reticuloendothelial system and it occurs in the liver, adipose tissue and in lung. It acts as an antioxidant and has antibacterial activity. Haptoglobin plays an important role in modulating many aspects of the acute phase response.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

Protocols

Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detection methods, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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Peer-Reviewed Papers
15

References

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