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GW21065 Sigma-Aldrich

Anti-LTBR antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Synonym: Anti-Lymphotoxin β receptor, Anti-TNFRSF3, Anti-Tumor necrosis factor receptor superfamily member 3



Related Categories A to L, Alphabetical Index, Antibodies, Antibodies for Apoptosis, Antibodies for Cell Biology,
conjugate   unconjugated
clone   polyclonal
biological source   chicken
application(s)   western blot: suitable
species reactivity   human
form   buffered aqueous solution
shipped in   wet ice
storage temp.   −20°C
antibody form   affinity isolated antibody
Quality Level   200
antibody product type   primary antibodies
mfr. no.   Genway, 15-288-21065
NCBI accession no.   NP_002333.1
UniProt accession no.   P36941
Gene Information   human ... LTBR(4055)


General description

LTBR (lymphotoxin β receptor) is a member of the tumor necrosis factor (TNF) superfamily, which also includes LTα and LTβ. It is expressed on stromal, parenchymal and myeloid cells. It is a part of the noncanonical/canonical nuclear factor-κB (NF-κB) signaling pathway.


Immunogen Sequence: GI # 4505039, sequence 106-159

Recombinant lymphotoxin β receptor


Anti-LTBR antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Biochem/physiol Actions

Lymphotoxin β receptor signaling serves pleiotropic functions including the control of lymphoid organ development and support of efficient immune responses against pathogens. LTBR signaling induces chemokine, cytokine or adhesion molecule expression, cell proliferation and cell survival. LTBR is important for development and organization of the secondary lymphoid tissues and its polymorphisms may be associated with risk of IgA nephropathy (IgAN).

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles


Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
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Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detection methods, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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