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  • GW21074 - Anti-Platelet Basic Protein antibody produced in chicken

GW21074 Sigma-Aldrich

Anti-Platelet Basic Protein antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Synonym: Anti-CXCL7, Anti-SCYB7, Anti-Small inducible cytokine B7

  •  NACRES NA.41



Related Categories Alphabetical Index, Antibodies, IgY Antibodies, M to Z, PJ-PN,
conjugate   unconjugated
clone   polyclonal
biological source   chicken
application(s)   western blot: suitable
species reactivity   human
form   buffered aqueous solution
shipped in   wet ice
storage temp.   −20°C
antibody form   affinity isolated antibody
Quality Level   200
antibody product type   primary antibodies
mfr. no.   Genway, 15-288-21074
NCBI accession no.   NP_002695.1
UniProt accession no.   P02775
Gene Information   human ... PPBP(5473)


General description

PPBP (pro-platelet basic protein), also called CXCL7 (chemokine (C-X-C motif) ligand 7), is synthesized as a pro-peptide, which has a molecular weight of 14kDa. It undergoes proteolytic cleavage to produce multiple forms with different biological activities. The longest form produced post cleavage is called PPBP or LDGF (leukocyte-derived growth factor), and is a mitogen for fibroblast cells.


Immunogen Sequence: GI # 4505981, sequence 50-96

Recombinant pro-platelet basic protein


Anti-Platelet Basic Protein antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Biochem/physiol Actions

PPBP (pro-platelet basic protein), also called chemokine (C-X-C motif) ligand 7 (CXCL7), plays a role in immune response of human phagocytes against the intracellular bacteria. It is found at a significantly higher level in patients with rheumatoid arthritis, which is a chronic inflammatory disease. CXCL7 may act as a helper marker in the follow-up and treatment of developing cardiovascular risk.

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles


Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy


Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detection methods, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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