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  • GW21249 - Anti-C13orf12 antibody produced in chicken

GW21249 Sigma-Aldrich

Anti-C13orf12 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Synonym: Anti-Chromosome 13 open reading frame 12, Anti-HSPC036 protein

  •  NACRES NA.41



Related Categories A to L, Alphabetical Index, Antibodies, C1-C19, IgY Antibodies,
conjugate   unconjugated
clone   polyclonal
biological source   chicken
application(s)   western blot: suitable
species reactivity   human, rat, mouse
form   buffered aqueous solution
shipped in   wet ice
storage temp.   −20°C
antibody form   affinity isolated antibody
Quality Level   200
antibody product type   primary antibodies
mfr. no.   Genway, 15-288-21249
NCBI accession no.   NP_057016.1
UniProt accession no.   Q9Y244
Gene Information   human ... C13orf12(51371)


General description

C13orf12, also called POMP (proteasome maturation protein), is a chaperone protein for proteasome, and has a molecular weight of 16kDa. It is thought to exist as a tetramer with the molecular weight of 64kDa. It is both a cytosolic and a nuclear protein. It has a ubiquitous expression pattern, and the corresponding gene is localized to human chromosome 13q.


Immunogen Sequence: GI # 7705429, sequence 1-141

Recombinant proteasome maturation protein


Anti-C13orf12 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biochem/physiol Actions

POMP (proteasome maturation protein), or C13orf12, acts as a chaperone which is essential for the maturation of the 20S proteasome proteolytic core complex. It has an important role in the terminal differentiation of human epidermis. Deletion in this gene is linked with KLICK syndrome, which is a rare autosomal-recessive skin disorder. The deletion results in modified distribution of proteasome in the epidermis, causing altered formation of outer layers of skin.

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles


Antibody Basics

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Western Blot Protocol | Immunoblotting Protocol

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Keywords: AGE, Buffers, Cell disruption, Detection methods, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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