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GW21260 Sigma-Aldrich

Anti-DPRP2 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Synonym: Anti-Dipeptidyl peptidase IV-related protein-2

  •  NACRES NA.41

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Properties

Related Categories A to L, Alphabetical Index, Antibodies, DM-DP, IgY Antibodies,
conjugate   unconjugated
clone   polyclonal
biological source   chicken
application(s)   western blot: suitable
species reactivity   human
form   buffered aqueous solution
shipped in   wet ice
storage temp.   −20°C
antibody form   affinity isolated antibody
Quality Level   200
antibody product type   primary antibodies
mfr. no.   Genway, 15-288-21260
NCBI accession no.   NP_631898.1
UniProt accession no.   O75273
Gene Information   human ... DPRP2(91039)

Description

General description

DPRP2 (dipeptidyl peptidase IV-related protein-2), also called DPP9 (dipeptidyl-peptidase 9), is a soluble cytoplasmic prolyl-peptidase, which is not well characterized. It is a proline cleaving peptidase, which belongs to the S9B/ DPPIV family. It is an exopeptidase, which cleaves off dipeptides from proteins at the second proline (Xaa-Pro) on the N-terminal side. In vertebrates it is ubiquitously expressed, and shares 60% sequence similarity with DPP8.

Immunogen

Immunogen Sequence: GI # 21040237, sequence 426-519

Recombinant dipeptidylpeptidase 9; dipeptidyl peptidase 9

Application

Anti-DPRP2 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biochem/physiol Actions

Dipeptidyl peptidase 9 is involved in various cellular pathways including amino acid recycling, antigen maturation, cellular homeostasis, and viability. DPP9 plays an important role in the regulation of survival and proliferation pathways. It also plays a crutial role in peptide turnover and antigen presentation. DPP9 have unique peptidase and extra-enzymatic activities that have been implicated in various diseases including cancers.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

Protocols

Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detection methods, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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Peer-Reviewed Papers
15

References

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