• USA Home
  • GW21361 - Anti-ITGB7 antibody produced in chicken

EMAIL THIS PAGE TO A FRIEND
GW21361 Sigma-Aldrich

Anti-ITGB7 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Synonym: Anti-Integrin β-7

Purchase

Properties

Related Categories A to L, Alphabetical Index, Antibodies, IQ-IZ, IgY Antibodies,
conjugate   unconjugated
clone   polyclonal
biological source   chicken
application(s)   western blot: suitable
species reactivity   human
form   buffered aqueous solution
shipped in   wet ice
storage temp.   −20°C
antibody form   affinity isolated antibody
antibody product type   primary antibodies
mfr. no.   Genway, 15-288-21361
NCBI accession no.   NP_000880.1
UniProt accession no.   P26010
Gene Information   human ... ITGB7(3695)

Description

Immunogen

Immunogen Sequence: GI # 4504777, sequence 67-136

Recombinant integrin, β 7

Application

Anti-ITGB7 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biochem/physiol Actions

Integrin β-7 is an integrin protein encoded by the ITGB7 gene in humans. The β7 subunit protein is associated with two integrin α subunits on lymphocytes. One β7 integrin and α4 β7, mediate lymphocyte adhesion to endothelium and to fibronectin. ITGB7 is expressed on naive B cells and memory B cells that traffic to the gastrointestinal tract. The integrins are a large family of heterodimeric cell-surface glycoproteins and play a key role in the adherence of cells to other cells and to extracellular matrix proteins. ITGB7 is also expected to play a role in adhesive interactions of leukocytes. Ligation of β(7) can inhibit the induction of CD38 expression.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

Protocols

Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detection methods, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

Related Content

Antibody Explorer | Buy Primary Antibodies & Secondary Antibodies

Primary, Secondary and Recombinant Monoclonal Antibodies Providing highly cited primary and secondary antibodies, we have you covered for your ELISA, western blot, immunohistochemistry or other assay...
Keywords: Alzheimer Disease, Cancer, Chromatin immunoprecipitation, Diagnostic, Enzyme-linked immunosorbent assay, Flow cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Neuroscience, Western blot

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?