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  • GW21429 - Anti-ADAM23 antibody produced in chicken

GW21429 Sigma-Aldrich

Anti-ADAM23 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Synonym: Anti-A disintegrin and metalloproteinase domain 23

  •  NACRES NA.41



Related Categories A to L, AD-AD, Alphabetical Index, Antibodies, IgY Antibodies,
conjugate   unconjugated
clone   polyclonal
biological source   chicken
application(s)   western blot: suitable
species reactivity   human
form   buffered aqueous solution
shipped in   wet ice
storage temp.   −20°C
antibody form   affinity isolated antibody
Quality Level   200
antibody product type   primary antibodies
mfr. no.   Genway, 15-288-21429
NCBI accession no.   NP_003803.1
UniProt accession no.   O75077
Gene Information   human ... ADAM23(8745)



Immunogen Sequence: GI # 4501913, sequence 72-144

Recombinant ADAM metallopeptidase domain 23 preproprotein


Anti-ADAM23 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Biochem/physiol Actions

Disintegrin and metalloproteinase domain-containing protein 23 is an enzyme encoded by the ADAM23 gene in humans and is a member of a disintegrin and metalloprotease (ADAM) family. It is higly expressed in the brain and may function as integrin ligands in the brain along with other proteins. ADAM23 is associated with the progression of non-small-cell lung carcinoma (NSCLC) and its downregulation may be correlated with promoter methylation. It may be down-regulated by aberrant promoter hypermethylation during the progression of colorectal cancer. ADAM23 is down-regulated by methylation in brain tumors, which is a rare event.

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles


Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy


Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detection methods, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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