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GW21448A Sigma-Aldrich

Anti-APEB2 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Synonym: Anti-AP-3 complex subunit β-2

  •  NACRES NA.41

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Properties

Related Categories A to L, AO-AQ, Alphabetical Index, Antibodies, IgY Antibodies,
conjugate   unconjugated
clone   polyclonal
biological source   chicken
application(s)   immunocytochemistry: suitable
  western blot: suitable
species reactivity   human
form   buffered aqueous solution
shipped in   wet ice
storage temp.   −20°C
antibody form   affinity isolated antibody
Quality Level   200
antibody product type   primary antibodies
mfr. no.   Genway, 15-288-21448A
NCBI accession no.   NP_004635.1
UniProt accession no.   Q13367
Gene Information   human ... AP3B2(8120)

Description

Immunogen

Immunogen Sequence: GI # 4758760, sequence 259-350

Recombinant adaptor-related protein complex 3, β 2 subunit

Application

Anti-APEB2 antibody produced in chicken is suitable for immunocytochemistry and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biochem/physiol Actions

AP-3 complex subunit β-2 is a protein encoded by the AP3B2 gene in humans. Adaptor protein 3 (AP-3) is a vesicle-coat protein that forms a heterotetrameric complex and consists of two subunits found in mammalian cells. Ubiquitous AP-3 subunits are expressed in all tissues of the body and neuronal AP-3 subunits may serve neuron-specific functions such as neurotransmitter release. AP-3 seems to localize in the trans-Golgi network and possibly immature secretory vesicles, where it may be involved in the formation of neurosecretory vesicles. It is involved in signal-mediated protein sorting to endosomal-lysosomal organelles and may be dependent on clathrin.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

Protocols

Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detection methods, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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Peer-Reviewed Papers
15

References

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