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  • GW22307B - Anti-ADFP (ab2) antibody produced in chicken

GW22307B Sigma-Aldrich

Anti-ADFP (ab2) antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

  •  NACRES NA.41



Related Categories A to L, AD-AD, Alphabetical Index, Antibodies, IgY Antibodies,
conjugate   unconjugated
clone   polyclonal
biological source   chicken
application(s)   western blot: suitable
species reactivity   human, mouse
form   buffered aqueous solution
shipped in   wet ice
storage temp.   −20°C
antibody form   affinity isolated antibody
Quality Level   200
antibody product type   primary antibodies
mfr. no.   Genway, 15-288-22307B
NCBI accession no.   NP_001113.2
UniProt accession no.   Q5SYF3
Gene Information   human ... ADFP(123)


General description

ADFP (adipose differentiation-related protein) is a mammalian lipid droplet protein, which coats lipid droplet surfaces. It is however absent from mature white adipocytes. It is also called perilipin 2 (PLIN2), and is a member of the PAT (perilipin, adipophilin, and the tail-interacting protein 47kDa) family of proteins, which includes five members. It has a predominant expression in skeletal muscles, in type I fibres.


Immunogen Sequence: GI # 34577059, sequence 241-437

Recombinant adipose differentiation-related protein


Anti-ADFP (ab2) antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biochem/physiol Actions

Adipose differentiation-related protein (ADFP) plays a novel role in the regulation of macrophage autophagy during lipopolysaccharide (LPS) stimulation. ADFP is the most abundant lipid droplet (LD)-associated protein found in non-adipose tissue and its expression correlates with intracellular lipid accumulation. Its polymorphism may affect its function and influence the development of metabolic and cardiovascular diseases. It has been observed that prolonged endurance-type exercise training increases the expression of ADFP leading to increases in intramuscular triglyceride (IMTG) content in a type I muscle fiber-type specific manner in type 2 diabetes patients.

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles


Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
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Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detection methods, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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