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GW22419A Sigma-Aldrich

Anti-PSMB7 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

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Properties

Related Categories Alphabetical Index, Antibodies, IgY Antibodies, M to Z, PS-PS,
conjugate   unconjugated
clone   polyclonal
biological source   chicken
application(s)   western blot: suitable
species reactivity   human, rat, mouse
form   buffered aqueous solution
shipped in   wet ice
storage temp.   −20°C
antibody form   affinity isolated antibody
antibody product type   primary antibodies
mfr. no.   Genway, 15-288-22419A
NCBI accession no.   NP_002790.1
UniProt accession no.   Q5TBG6
Gene Information   human ... PSMB7(5695)

Description

General description

PSMB7 (proteasome subunit β7) is a component of proteasome, which is a multi-catalytic protease complex. It has a ring shaped 20S proteasome core region, which contains 28 non-identical subunits divided into four rings. Seven α subunits make up two rings, and seven β subunits make up the other two rings. PSMB7 is one of the β subunits.

Immunogen

Immunogen Sequence: GI # 4506203, sequence 151-277

Recombinant proteasome β 7 subunit proprotein

Application

Anti-PSMB7 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Biochem/physiol Actions

Proteasome subunit β type-7 (PSMB7) plays a major role in non-lysosomal proteolysis and in the processing of proteins for presentation by the MHC class I pathway. Proteasome exists in several distinct molecular forms, which contribute to the different functions. Overexpression is an unfavourable prognostic marker in breast cancer. PSMB7 is significantly associated with the occurrence of fetal loss.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2

Documents

Certificate of Analysis

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Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

Protocols

Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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Peer-Reviewed Papers
15

References

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