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  • GW22461F - Anti-Interleukin-2 antibody produced in chicken

GW22461F Sigma-Aldrich

Anti-Interleukin-2 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

  •  NACRES NA.41



Related Categories A to L, Alphabetical Index, Analytical Cytology, Antibodies, Antibodies for Cell Biology,
conjugate   unconjugated
clone   polyclonal
biological source   chicken
application(s)   indirect ELISA: suitable
  western blot: suitable
species reactivity   rat, mouse, human
form   buffered aqueous solution
shipped in   wet ice
storage temp.   −20°C
antibody form   affinity isolated antibody
Quality Level   200
antibody product type   primary antibodies
mfr. no.   Genway, 15-288-22461F
NCBI accession no.   NP_000577.2
UniProt accession no.   P60568
Gene Information   human ... IL2(3558)


General description

IL2 (interleukin 2) is a pro-inflammatory cytokine, which is predominantly synthesized by activated T-cells and dendritic cells (DCs). T-cells also act as effector of IL-2 as they contain the interleukin 2 receptor (IL2R). This gene is localized to human chromosome 4q27, and codes for a glycoprotein with a molecular weight of 14-17kDa.


Immunogen Sequence: GI # 28178861, sequence 1-153

Recombinant interleukin 2


Anti-Interleukin-2 antibody produced in chicken is suitable for the production of anti-IL2 surface-conjugated microtoroids. It is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biochem/physiol Actions

Interleukin 2 (IL-2) is an interleukin and is a cytokine signaling molecule in the immune system. It plays an important role in signal transduction for biological functions of IL-2. Upregulation of IL-2 combined with activation of IL-2-dependent signaling pathways may contribute to the pathogenesis of Focal cortical dysplasia (FCD). Aerosol interleukin-2 (IL-2) increases the number of intravenously injected human natural killer (NK) cells in the lungs by stimulating local NK cell proliferation. The effect on NK cell proliferation is organ specific, which makes it ideal for the specific targeting of lung metastasis.

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles


Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy


Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detection methods, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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