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GW22478 Sigma-Aldrich

Anti-CEACAM5 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution



Related Categories A to L, Alphabetical Index, Antibodies, CE-CH, IgY Antibodies,
conjugate   unconjugated
clone   polyclonal
biological source   chicken
application(s)   western blot: suitable
species reactivity   human
form   buffered aqueous solution
shipped in   wet ice
storage temp.   −20°C
antibody form   affinity isolated antibody
Quality Level   200
antibody product type   primary antibodies
mfr. no.   Genway, 15-288-22478
NCBI accession no.   NP_004354.1
UniProt accession no.   P06731
Gene Information   human ... CEACAM5(1048)


General description

CEACAM5 (carcinoembryonic antigen-related cell adhesion molecule 5) is a member of the CEACAM receptors, which in turn belong to immunoglobulin (Ig) superfamily. Its N-terminal contains an Ig variable-region-like domain, which is succeeded by multiple Ig constant-region-like domains. The latter domains protrude into the exoplasmic space. It is expressed by the squamous epithelial cells of the female genital tract.


Immunogen Sequence: GI # 11386171, sequence 460-600

Recombinant carcinoembryonic antigen-related cell adhesion molecule 5


Anti-CEACAM5 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biochem/physiol Actions

Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5 OR CEA) is expressed by cancer cells. It is considered as an independent tumor marker in monitoring metastatic colorectal cancer and can be detected in the blood serum. CEA acts as a prognostic marker for malignant diseases (such as early-stage non-small cell lung cancer (NSCLC)). Increase in serum CEA may be attributed to the presence of local inflammation in the lung. CEA level may be a suitable biomarker for predicting tumor response.

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles


Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy


Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detection methods, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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