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  • GW22677 - Anti-DLG7 antibody produced in chicken

GW22677 Sigma-Aldrich

Anti-DLG7 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

  •  NACRES NA.41



Related Categories A to L, Alphabetical Index, Antibodies, DE-DL, IgY Antibodies,
conjugate   unconjugated
clone   polyclonal
biological source   chicken
application(s)   western blot: suitable
species reactivity   human
form   buffered aqueous solution
shipped in   wet ice
storage temp.   −20°C
antibody form   affinity isolated antibody
Quality Level   200
antibody product type   primary antibodies
NCBI accession no.   NP_055565.2
UniProt accession no.   Q15398
Gene Information   human ... DLGAP5(9787)


General description

DLGAP5 (discs large homolog-associated protein 5) or DLG7, acts as a mitotic phosphoprotein substrate for Aurora-A. It was recognized 10 years ago, and is a Ser/Thr kinase, which is modulated by cell cycle. It contains a highly conserved domain called guanylate-kinase-associated protein (GKAP) guanylate-kinase-associated protein (GKAP). It is localized to cytoplasm, and is highly expressed in fetal liver. In adults, its predominant expression is in bone marrow, colon, testis and placenta.


Immunogen Sequence: GI # 21361645, sequence 1-300

Recombinant discs large homolog 7


Anti-DLG7 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Biochem/physiol Actions

The expression of discs large-associated protein 5 (DAP-5, also known as DLG7) is hypoxia-controlled and holds prognostic potential in high-risk prostate cancer (CaP). It can act as a novel biomarker for prostate cancer (CaP). Expression of DLGAP5 is regulated by methylation and the up-regulation contributes to hepatocellular carcinoma tumorigenesis by promoting cell proliferation. It is useful for non-invasive test for early detection of bladder cancer and bilharzial bladder cancer.

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles


Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
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Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detection methods, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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