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GW22823 Sigma-Aldrich

Anti-BAT3 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

  •  NACRES NA.41

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Properties

Related Categories A to L, Alphabetical Index, Antibodies, B-BI, IgY Antibodies,
conjugate   unconjugated
clone   polyclonal
biological source   chicken
application(s)   western blot: suitable
species reactivity   rat, human
form   buffered aqueous solution
shipped in   wet ice
storage temp.   −20°C
antibody form   affinity isolated antibody
Quality Level   200
antibody product type   primary antibodies
mfr. no.   Genway, 15-288-22823
NCBI accession no.   NP_542434.1
UniProt accession no.   P46379
Gene Information   human ... BAT3(7917)

Description

General description

BAT3 is a gene from major histocompatibility complex. In humans, it is localized in the class III region of the human major histocompatibility complex on chromosome 6. It consists of an ubiquitin homology region at the N-terminal end, short tracts of polyproline and polyglycine, a zinc finger-like domain and a nuclear localization signal (NLS) at the C- terminus end. It is a member of BAG family of proteins. The major responsibility of BAG proteins is to negatively control the chaperone function of the Hsp70 family.

Immunogen

Immunogen Sequence: GI # 18375632, sequence 2-250

Recombinant HLA-B associated transcript-3 isoform b

Application

Anti-BAT3 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biochem/physiol Actions

Large proline-rich protein BAT3 is a protein encoded by the BAT3 gene in humans. It is very rich in proline and includes short tracts of polyproline, polyglycine and charged amino acids. BAT3 is similar to other proteins with large proline-rich domains, such as some nuclear proteins, collagens, elastin and synapsin. It has distinct functions in the cytosol and in the nucleus. It is also associated with controlling of apoptosis and regulating heat shock protein (HSP) 70 activity.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

Protocols

Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detection methods, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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Peer-Reviewed Papers
15

References

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