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H2775 Sigma-Aldrich

DL-threo-β-Hydroxyaspartic acid

Synonym: threo-2-Amino-3-hydroxysuccinic acid

  • CAS Number 4294-45-5

  • Empirical Formula (Hill Notation) C4H7NO5

  • Molecular Weight 149.10

  •  EC Number 224-299-4

  •  MDL number MFCD00036749

  •  eCl@ss 32160406

  •  PubChem Substance ID 24278465

  •  NACRES NA.32

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids, Neuroscience, Neurotransmission,
Quality Level   200
storage temp.   −20°C
SMILES string   N[C@H]([C@@H](O)C(O)=O)C(O)=O
InChI   1S/C4H7NO5/c5-1(3(7)8)2(6)4(9)10/h1-2,6H,5H2,(H,7,8)(H,9,10)/t1-,2-/m1/s1
InChI key   YYLQUHNPNCGKJQ-JCYAYHJZSA-N
Gene Information   human ... GLUL(2752)
mouse ... GLUL(14645)

Description

General description

DL-threo-β-hydroxyaspartic acid (THA) is a glutamate uptake inhibitor.

Application

DL-threo-β-Hydroxyaspartic acid (THA) has been used to block glutamate transport in cannulated sprague dawley rat.

Packaging

250 mg in glass bottle

50 mg in poly bottle

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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