• USA Home
  • H2779 - HistoChoice® Clearing Agent

H2779 Sigma-Aldrich

HistoChoice® Clearing Agent

Green Alternative

  •  NACRES NA.47



Related Categories 12 Principles Aligned Products, Chemical Synthesis, Greener Alternative Products, Greener Life Science Products
Quality Level   100
form   liquid
greener alternative product characteristics   Designing Safer Chemicals
Learn more about the Principles of Green Chemistry.
application(s)   hematology: suitable
  histology: suitable
color   colorless
density   0.760-0.820 g/mL
storage temp.   room temp


General description

HistoChoice® is a patented, complex mixture of agents that allow tissues to retain their structure, antigenic sites and nucleic acid sites. This formulation in non-citrus, contains no mercury, formaldehyde or glutaraldehyde.

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has Inherently Safer Chemistry, compared to the standard use of formalin for tissue processing.


HistoChoice® Clearing Agent is suitable as an alternative to toluene and xylene for dewaxing paraffin tissue sections. Prepared slides are suitable for antibody probing applications and in situ hybridizations.

Features and Benefits

• Non-toxic and odorless
• Preserves native antigenic and nucleic acid sites
• Tissues retain original structure

Legal Information

HistoChoice is a registered trademark of Amresco, Inc.

Safety & Documentation

Safety Information

GHS07  GHS07
Signal word 
Hazard statements 
Target organs 
Respiratory system
NA 1993 / PGIII
WGK Germany 
Flash Point(F) 
142.0 °F
Flash Point(C) 
61.1 °C


Certificate of Analysis (COA)

Please Enter a Lot Number

Certificate of Origin (COO)

Please Enter a Lot Number

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
Is HistoChoice Clearing Agent, product H2779,compatible with polycarbonate?
The supplier of HistoChoice Clearing Agent has reported no incompatibilities were observed when polycarbonate was exposed to HistoChoice Clearning Agent for at least 1 hour.
My question is not addressed here, how can I contact Technical Service for assistance?
Ask a Scientist here.
My question is not addressed here, how can I contact Technical Service for assistance?
Ask a Scientist here.
Show more questions
Protocols & Articles

Related Content

Greener Alternatives Four Categories

A new icon has been added to identify our Greener alternative products. Products with this icon fulfill one of the four criteria.
Keywords: Alternative energy, Environmental, Green chemistry, PAGE, Solvents, Substitutions

Peer-Reviewed Papers


Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?