• USA Home
  • H3128 - Calconcarboxylic acid

EMAIL THIS PAGE TO A FRIEND
H3128 Sigma-Aldrich

Calconcarboxylic acid

Synonym: 2-Hydroxy-1-(2-hydroxy-4-sulfo-1-naphthylazo)-3-naphthoic acid, 3-Hydroxy-4-(2-hydroxy-4-sulfo-1-naphthylazo)naphthalene-2-carboxylic acid, Patton and Reeder’s reagent

  • CAS Number 3737-95-9

  • Empirical Formula (Hill Notation) C21H14N2O7S

  • Molecular Weight 438.41

  •  Beilstein/REAXYS Number 727492

  •  EC Number 223-117-0

  •  MDL number MFCD00004078

  •  PubChem Substance ID 24895550

  •  NACRES NA.47

Purchase

Properties

Related Categories C, Cell Biology, Hematology and Histology, Stains & Dyes, A to Z, Stains and Dyes More...
Quality Level   100
form   powder
application(s)   hematology: suitable
  histology: suitable
mp   300 °C
solubility   1 M NaOH: 10 mg/mL
Featured Industry   Diagnostic Assay Manufacturing
storage temp.   room temp
SMILES string   OC(=O)c1cc2ccccc2c(N=Nc3c(O)cc(c4ccccc34)S(O)(=O)=O)c1O
InChI   1S/C21H14N2O7S/c24-16-10-17(31(28,29)30)13-7-3-4-8-14(13)18(16)22-23-19-12-6-2-1-5-11(12)9-15(20(19)25)21(26)27/h1-10,24-25H,(H,26,27)(H,28,29,30)/b23-22-
InChI key   MVQBFZXBLLMXGS-FCQUAONHSA-N

Description

General description

Calconcarboxylic acid is a useful indicator for calcium titrations with EDTA in the presence of magnesium. It is also required for the staining of proteins in gels.

Calconcarboxylic acid is also known as Patton-Reeder indicator and is used in the determination of calcium at pH 12. Calconcarboxylic acid is a chelating agent and is used in the preparation of chelating sorbent along with chemically modified silica LiChroprep-NH2, for trace metal analysis. Calconcarboxylic acid coupled with 3-aminopropyltriethoxysilane (APS-CCA), a fluorescent probe, facilitates the medical detection of Ca2+ ions in the blood with minimal blood backgrounds using hydrophobic hexadecyltrimethoxysilane (HDS) as substrate in fluorimetric microarray method.

Application

Calconcarboxylic acid (CCA) has been used in the preparation of poly-CCA film for leukemia diagnosis by immobilization, hybridization of DNA and detection by methylene blue and differential pulse voltammetry.

Packaging

5, 25, 100 g in glass bottle

Quality

Contains an inert diluent.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Target organs 
Respiratory system
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Certificate of Origin (COO)

Please Enter a Lot Number
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?