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H4792 Sigma-Aldrich

Cytochrome P450 2C9*1 (Wild type allele), human

recombinant, expressed in E. coli

Synonym: CYP2C9, Cytochrome P450, purified, soluble

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Properties

Related Categories Application Index, Biochemicals and Reagents, Cell Signaling Enzymes, Cytochrome P450 human recombinant purified soluble, Cytochrome P450s (CYPs),
Quality Level   200
biological source   human
recombinant   expressed in E. coli
description   purified, soluble
form   liquid
specific activity   12-88 units/mg protein
mol wt   54423.1 g/mol
concentration   3.5-25 mg protein/mL (protein)
  50-150 nmol/mL (P450)
  6-14 nmol/mg protein (specific content)
NCBI accession no.   NP_000762.2
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... CYP2C9(1559)

Description

General description

Supplied as purified soluble proteins, rather than microsomal preparations.

Unit Definition

One unit will convert 1.0 nanomole of diclofenac (2-(2,6-dichloranilino) phenylacetic acid) 4`-hydroxylated product per minute at pH 7.4 at 37 °C.

Other Notes

Visit our drug metabolism resources: www.sigmaaldrich.com/life-science/metabolomics/enzyme-explorer/cell-signaling-enzymes/xenobiotics.html

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
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