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H5142 Sigma-Aldrich

20-Hydroxyecdysone

≥93% (HPLC), powder

Synonym: β-Ecdysone, 2β,3β,14α,20β,22,25-Hexahydroxy-7-cholesten-6-one, Ecdysterone, Insect moulting hormone, Polypodine A

  • CAS Number 5289-74-7

  • Empirical Formula (Hill Notation) C27H44O7

  • Molecular Weight 480.63

  •  Beilstein/REAXYS Number 1917578

  •  MDL number MFCD00036740

  •  PubChem Substance ID 24895674

  •  NACRES NA.77

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Description

Application

20-Hydroxyecdysone has been used:
• in Leibovitz′s dissecting medium for culturing sorting zone and neuropil-associated glia and antennal lobes of Manduca sexta
• in Schneider′s medium to reproduce ex-vivo imaginal disc eversion
• as a supplement in Mcl8 medium for culturing Drosophila wing imaginal discs

Packaging

10, 25 mg in poly bottle

5 mg in glass bottle

Biochem/physiol Actions

20-Hydroxyecdysone is an ecdysteroid hormone that plays a key role in insect development, cell proliferaton, growth and apoptosis by controlling gene expression involved in molting and metamorphosis. It acts through a heterodimeric receptor comprising the ecdysone receptor and the ultraspiracle proteins (USP).

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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