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H5257 Sigma-Aldrich

Hispidin

solid, ≥98% (HPLC)

Synonym: 6-(3,4-dihydroxystyrl)-4-hydroxy-2-pyrone

  • CAS Number 555-55-5

  • Empirical Formula (Hill Notation) C13H10O5

  • Molecular Weight 246.22

  •  MDL number MFCD01866972

  •  PubChem Substance ID 24278468

  •  NACRES NA.77

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Properties

Related Categories Antitumor Agents, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Cancer Research,
assay   ≥98% (HPLC)
form   solid
storage condition   protect from light
color   yellow to brown
solubility   DMSO: >10 mg/mL
storage temp.   −20°C
SMILES string   OC1=CC(/C=C/C(O2)=CC(O)=CC2=O)=CC=C1O
InChI   1S/C13H10O5/c14-9-6-10(18-13(17)7-9)3-1-8-2-4-11(15)12(16)5-8/h1-7,14-16H/b3-1+
InChI key   SGJNQVTUYXCBKH-HNQUOIGGSA-N
Gene Information   human ... PRKACB(5567), PRKAR2B(5577), PRKCB(5579)

Description

General description

Hispidin is a phenolic compound, that is obtained from a medicinal mushroom, Phellinus linteus.

Packaging

5 mg in glass bottle

Biochem/physiol Actions

Hispidin exhibits robust antioxidant, anticancer and antidiabetic properties. It has the ability to guard against peroxynitrite-mediated cytotoxicity, DNA damage and the development of hydroxyl radicals.

Potent inhibitor of protein kinase Cβ, cytotoxic for cancer cells.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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