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H5417 Sigma

Cytochrome P450 2C19, human

recombinant, expressed in E. coli

Synonym: CYP2C19, Cytochrome P450, purified, soluble

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Properties

Related Categories Application Index, Biochemicals and Reagents, Cell Signaling Enzymes, Cytochrome P450 human recombinant purified soluble, Cytochrome P450s (CYPs),
recombinant   expressed in E. coli
description   purified, soluble
activity   12-110 units/mg protein
mol wt   mol wt 54783.3 g/mol
concentration   3.5-25 mg/mL protein
  50-150 nmol/mL (P450)
  6-14 nmol/mg protein (specific content)
NCBI accession no.   NP_00760.1
shipped in   dry ice
storage temp.   −70°C

Description

General description

Supplied as purified soluble proteins, rather than microsomal preparations.

Other Notes

Visit our drug metabolism resources: http://www.sigmaaldrich.com/life-science/metabolomics/enzyme-explorer/cell-signaling-enzymes/xenobiotics.html

Unit Definition

One unit will convert 1.0 nanomole of omeprazole (6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole) to 5-hydroxyomeprazole per minute at pH 7.4 at 37 °C.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Flash Point(F) 
320 °F
Flash Point(C) 
160 °C

Documents

Certificate of Analysis


Expore Enzymes, Proteins & Cofactors
Protocols & Articles
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