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H8653 Sigma-Aldrich

(±)-7-Hydroxy-2-(di-n-propylamino)tetralin hydrobromide

Synonym: (±)-7-Hydroxy-DPAT hydrobromide, (±)-7-OH-DPAT hydrobromide, (±)-2-Dipropylamino-7-hydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide

  • CAS Number 159795-63-8

  • Empirical Formula (Hill Notation) C16H25NO · HBr

  • Molecular Weight 328.29

  •  MDL number MFCD00153809

  •  PubChem Substance ID 24277938

  •  NACRES NA.32

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Properties

Related Categories Agonists, Cell Biology, Cell Signaling and Neuroscience, Dopaminergics, Neuroscience,
Quality Level   200
solubility   H2O: >15 mg/mL
storage temp.   2-8°C
SMILES string   Br.CCCN(CCC)C1CCc2ccc(O)cc2C1
InChI   1S/C16H25NO.BrH/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15;/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3;1H
InChI key   ODNDMTWHRYECKX-UHFFFAOYSA-N
Gene Information   human ... DRD3(1814)

Description

Packaging

25, 100 mg in poly bottle

Biochem/physiol Actions

(±)-7-Hydroxy-2-(di-n-propylamino)tetralin hydrobromide is a selective D3 dopamine receptor agonist (Kd <1nM); has much weaker affinity for other dopamine receptor subtypes.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Target organs 
Respiratory system
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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