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H9377 Sigma-Aldrich

Hypoxanthine

≥99.0%

Synonym: 6-Hydroxypurine

  • CAS Number 68-94-0

  • Empirical Formula (Hill Notation) C5H4N4O

  • Molecular Weight 136.11

  •  Beilstein/REAXYS Number 5811

  •  EC Number 200-697-3

  •  MDL number MFCD00005725

  •  PubChem Substance ID 24895850

  •  NACRES NA.51

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Properties

Related Categories Biochemicals and Reagents, Nucleoside Analogs, Nucleosides, Nucleotides, Oligonucleotides More...
Quality Level   200
biological source   synthetic (organic)
assay   ≥99.0%
form   powder
mp   >300 °C (lit.)
solubility   formic acid: water (2:1): 50 mg/mL, clear to slightly hazy, colorless to yellow
SMILES string   O=C1NC=Nc2nc[nH]c12
InChI   1S/C5H4N4O/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10)
InChI key   FDGQSTZJBFJUBT-UHFFFAOYSA-N

Description

Application

Hypoxanthine is a nutrient additive for a variety of cell culture applications involving bacterial, parasite (Plasmodium falciparum) and animal cells. Hypoxanthine is a component of selection media used in hybridoma technologies.

Hypoxanthine is the purine base of the nucleoside inosine. Hypoxanthine may be used as a substrate to study the specificity and kinetics of hypoxanthine-guanine phosphoribosyl transferases.

Packaging

1, 5, 25, 100 g in poly bottle

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
UP0791000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

HPLC Analysis of Xanthines on Purospher®STAR RP-18 endcapped

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Xanthines on Purospher®STAR RP-18 endcapped
Keywords: Chromatography, Clinical, High performance liquid chromatography, Pharmaceutical, Separation

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

TLC Analysis of Purine Derivatives on HPTLC NH2 F254s (analyte set 1)

From our library of Articles, Sigma-Aldrich presents TLC Analysis of Purine Derivatives on HPTLC NH2 F254s (analyte set 1)
Keywords: Thin layer chromatography

TLC Analysis of Purine Derivatives on HPTLC NH2 F254s (analyte set 2)

From our library of Articles, Sigma-Aldrich presents TLC Analysis of Purine Derivatives on HPTLC NH2 F254s (analyte set 2)
Keywords: Thin layer chromatography

Related Content

Uric Acid in Cell Culture

Importance and uses of uric acid (urate) precursors in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures
Keywords: Apoptosis, Cell culture, Culture media, High performance liquid chromatography, Lipid peroxidation, Nitrations, Oxidations, Peroxidations, Reductions

Peer-Reviewed Papers
15

References

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