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I0911 Sigma-Aldrich

IRR (945-end), active, GST tagged human

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym: INSRR

  •  NACRES NA.32

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Properties

Related Categories Active Kinases, Application Index, Biochemicals and Reagents, Cell Biology, Cell Signaling Enzymes,
Quality Level   200
recombinant   expressed in baculovirus infected Sf9 cells
product line   PRECISIO® Kinase
assay   ≥70% (SDS-PAGE)
form   buffered aqueous glycerol solution
activity   94-128 nmol/min·mg
mol wt   ~65 kDa
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... INSRR(3645)

Description

General description

IRR (insulin receptor-related receptor) belongs to the insulin receptor (IR) family. It is expressed in neuronal tissues, kidney, pancreas and stomach.

Biochem/physiol Actions

IRR or insulin receptor-related receptor is a tyrosine protein kinase. IRR is an extracellular pH sensor. The IRR mRNA is present in neuroblastomas and may be associated with tumor genesis.

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

Legal Information

PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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