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I110 Supelco

Ibuprofen

Synonym: α-Methyl-4-(isobutyl)phenylacetic acid, (±)-2-(4-Isobutylphenyl)propanoic acid

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Properties

Related Categories Additional Drugs, Analytical Standards, Analytical/Chromatography, Arachidonic Acid Cascade, Cell Biology,
Quality Level   100
assay   ≥98% (HPLC)
form   neat
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
color   white to off-white
Featured Industry   Forensics and Toxicology
Pharmaceutical (small molecule)
format   neat
SMILES string   CC(C)Cc1ccc(cc1)C(C)C(O)=O
InChI   1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)
InChI key   HEFNNWSXXWATRW-UHFFFAOYSA-N
Gene Information   human ... PTGS1(5742), PTGS2(5743)

Description

General description

Ibuprofen is a non-steroidal and anti-inflammatory drug, which finds a variety of therapeutic applications in relieving pain and inflammatory disorders.

Application

Ibuprofen has been used as a test compound in studying its removal from aqueous solutions via adsorption on titanium dioxide based multi-walled carbon nanotube membranes. It is also used as an external reference standard in order to validate the purity of the macro-cyclic peptides, an emerging therapeutic drug modality, using nuclear magnetic resonance technique (NMR).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

1, 5 g in poly bottle

Biochem/physiol Actions

Cyclooxygenase (COX) inhibitor that has greater activity against COX-1 than against COX-2.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
MU6640000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

HPLC Analysis of Acetaminophen, Caffeine, Chlorpheniramine, Ibuprofen, Naproxen, Phenylephrine, and Pseudoephedrine on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Acetaminophen, Caffeine, Chlorpheniramine, Ibuprofen, Naproxen, Phenylephrine, and Pseudoephedrine on Ascentis® Express C18
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical, Separation

HPLC Analysis of Acidic and Neutral Drug Panel on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Acidic and Neutral Drug Panel on Ascentis® Express C18
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Hormones, Pharmaceutical

HPLC Analysis of Anti-Inflammatory Drugs on Discovery® RP-Amide C16

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Anti-Inflammatory Drugs on Discovery® RP-Amide C16
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Ibuprofen Enantiomers on Astec® CHIROBIOTIC® V

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Ibuprofen Enantiomers on Astec® CHIROBIOTIC® V
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of NSAIDs on Ascentis® RP-Amide

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of NSAIDs on Ascentis® RP-Amide
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of NSAIDs on Discovery® Zr-Carbon C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of NSAIDs on Discovery® Zr-Carbon C18
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

Peer-Reviewed Papers
15

References

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