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I1149 Sigma-Aldrich

Iodoacetamide

BioUltra

  • CAS Number 144-48-9

  • Linear Formula ICH2CONH2

  • Molecular Weight 184.96

  •  Beilstein/REAXYS Number 1739080

  •  EC Number 205-630-1

  •  MDL number MFCD00008028

  •  PubChem Substance ID 24278486

  •  NACRES NA.77

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Properties

Related Categories A to C, Biochemicals and Reagents, Carnitine acetyltransferase, Core Bioreagents, D to K,
Quality Level   300
biological source   synthetic (organic)
product line   BioUltra
assay   ≥99% (NMR)
form   powder
impurities   ≤0.0005% Phosphorus (P)
  ≤0.1% Insoluble matter
mp   92-95 °C (lit.)
solubility   H2O: 0.5 M, clear, colorless
anion traces   chloride (Cl-): ≤0.05%
  sulfate (SO42-): ≤0.05%
cation traces   Al: ≤0.0005%
  Ca: ≤0.0005%
  Cu: ≤0.0005%
  Fe: ≤0.0005%
  K: ≤0.005%
  Mg: ≤0.0005%
  NH4+: ≤0.05%
  Na: ≤0.05%
  Pb: ≤0.001%
  Zn: ≤0.0005%
storage temp.   2-8°C
SMILES string   NC(=O)CI
InChI   1S/C2H4INO/c3-1-2(4)5/h1H2,(H2,4,5)
InChI key   PGLTVOMIXTUURA-UHFFFAOYSA-N

Description

Packaging

5, 25, 100 g in glass bottle

Application

Alkylating reagent for cysteine residues in peptide sequencing. By virtue of reaction with cysteine, it is an irreversible inhibitor of enzymes with cysteine at the active site. It reacts much more slowly with histidine residues, but that activity is responsible for inhibition of ribonuclease.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Target organs 
Respiratory system
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
WGK 3
RTECS 
AC4200000

pHast Pack
Protocols & Articles
Peer-Reviewed Papers
15

References

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