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I138 Sigma-Aldrich

1,5-Isoquinolinediol

≥98% (HPLC), powder

Synonym: 1,5-Dihydroxyisoquinoline, 5-Hydroxy-1(2H)-isoquinolinone, DiQ

  • CAS Number 5154-02-9

  • Empirical Formula (Hill Notation) C9H7NO2

  • Molecular Weight 161.16

  •  MDL number MFCD00006900

  •  PubChem Substance ID 24278174

  •  NACRES NA.77

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Properties

Related Categories Apoptosis and Cell Cycle, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology,
assay   ≥98% (HPLC)
form   powder
color   white to beige
mp   279-281  °C
solubility   DMSO: 20 mg/mL, clear
storage temp.   2-8°C
SMILES string   Oc1cccc2c(O)nccc12
InChI   1S/C9H7NO2/c11-8-3-1-2-7-6(8)4-5-10-9(7)12/h1-5,11H,(H,10,12)
InChI key   LFUJIPVWTMGYDG-UHFFFAOYSA-N

Description

Packaging

5, 100 mg in glass bottle

Biochem/physiol Actions

DiQ is a potent inhibitor of Poly(ADP-ribose) synthetase which is activated by nitric oxide; neuroprotective agent.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Caution

Light sensitive

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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