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I1774 Sigma-Aldrich

Iturin A from Bacillus subtilis

≥95% (HPLC)

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Properties

Related Categories Antibiotics, Antibiotics A to Z, Antibiotics G-M, Antibiotics by Mechanism of Action, Antifungal,
assay   ≥95% (HPLC)
solubility   ethanol: soluble 9.80-10.20 mg/mL
Mode of action   cell membrane | interferes
antibiotic activity spectrum   fungi
storage temp.   2-8°C

Description

Application

Iturin A was used in the study of Bacillomycin D (an iturin with antifungal activity against Aspergillus flavus).

Packaging

1, 5 mg in glass bottle

Biochem/physiol Actions

IturinA exhibits strong antifungal activity against pathogenic yeast and fungi. It interacts with the cytoplasmic membrane of the target cell forming ion conducting pores. Its mode of action could be attributed to its interaction with sterols and phospholipids. The compound causes the release of exo-vesicles from human erythrocytes.

Other Notes

A family of lipopeptides characterized by a heptapeptide cyclized with a C13-C17 β-amino fatty acid. Composed mainly of C14-C15 β-amino acids.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Protocols & Articles
Peer-Reviewed Papers
15

References

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