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I2512 Sigma

Sodium iodoacetate

≥98%

Synonym: Iodoacetic acid sodium salt

  • CAS Number 305-53-3

  • Linear Formula ICH2COONa

  • Molecular Weight 207.93

  •  Beilstein Registry Number 4009322

  •  EC Number 206-165-7

  •  MDL number MFCD00002686

  •  PubChem Substance ID 24895977

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Description

Packaging

25, 100 g in glass bottle

Application

Reagent for the modification of cysteine residues in proteins. Used in protein sequencing (including by Sanger in sequencing bovine insulin) to prevent oxidation of -SH sidechains.

Reagent for the modification of cysteine residues in proteins. Used to induce animal osteoarthritis model system, which mimics both symptoms and histopathology of the human disease.

Biochem/physiol Actions

Used to induce osteoarthritis-like lesions and functional impairment in rats, for testing of chondroprotective agents and diagnostic imaging techniques.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
RTECS 
AI3675000

Documents

Certificate of Analysis

Certificate of Origin


Expore Enzymes, Proteins & Cofactors

Stabilizer Protein and RNA Stabilization Reagents
Protocols & Articles
Peer-Reviewed Papers
15

References

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