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I2661 Sigma-Aldrich

Interleukin-4 human

IL-4, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), animal component free

Synonym: IL-4, B cell stimulatory factor-1 (BSF-1), mast cell growth factor-2 (MCGF-2), T cell growth factor-2 (TCGF-2) human

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Properties

Related Categories Cell Culture, Growth Factors and Cytokines, Interleukin-4, Interleukins (IL), Reagents and Supplements More...
biological source   human
recombinant   expressed in E. coli
assay   ≥98% (SDS-PAGE)
form   lyophilized powder
potency   ≤0.4 ng/mL EC50
mol wt   14.9  kDa
storage condition   avoid repeated freeze/thaw cycles
impurities   ≤1 EU/μg protein Endotoxin
color   white
solubility   water: soluble 0.100 mL, clear, colorless
UniProt accession no.   P05112
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... IL4(3565)

Description

Biochem/physiol Actions

Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including differentiation of naive T cells into the TH2 phenotype, promoting B cell proliferation, antibody isotype switching, and expression of other TH2 cytokines including IL-5 and IL-9. IL-4 plays a critical role in the development of allergic inflammation and asthma.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2

Pipette Controller from Brand
Protocols & Articles

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Peer-Reviewed Papers
15

References

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