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  • I2760 - (−)-Isoproterenol (+)-bitartrate salt

I2760 Sigma-Aldrich

(−)-Isoproterenol (+)-bitartrate salt


Synonym: (−)-Isoprenaline (+)-bitartrate salt

  • CAS Number 54750-10-6

  • Empirical Formula (Hill Notation) C11H17NO3 · C4H6O6

  • Molecular Weight 361.34

  •  MDL number MFCD00069361

  •  PubChem Substance ID 24277773

  •  NACRES NA.77



Related Categories Adrenergics, Adrenergics - Agonists, Agonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index,
Quality Level   200
form   powder
color   white to off-white
solubility   H2O: ≥50 mg/mL, clear, colorless to faintly yellow
originator   Sanofi Aventis
SMILES string   O[C@@H]([C@H](O)C(O)=O)C(O)=O.CC(C)NC[C@H](O)c1ccc(O)c(O)c1
InChI   1S/C11H17NO3.C4H6O6/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;5-1(3(7)8)2(6)4(9)10/h3-5,7,11-15H,6H2,1-2H3;1-2,5-6H,(H,7,8)(H,9,10)/t11-;1-,2-/m00/s1
Gene Information   human ... ADRB1(153), ADRB2(154), ADRB3(155)



(−)-Isoproterenol (+)-bitartrate salt has been used:
• as a component in KRH medium for cyclic adenosine monophosphate (cAMP) assay
• to stimulate preadipocytes to study its concentration responsive curve
• to intraperitoneally administer to mice to evaluate whether the multi-dry-electrode plate (MDEP)-sensor system can assess drug responses


1 g in ampule

100, 500 mg in ampule

Biochem/physiol Actions

Isoproterenol functions as an ovine pulmonary vein dilator.

β-Adrenoceptor agonist; increases cytosolic cAMP.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

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Safety & Documentation

Safety Information

GHS07  GHS07
Signal word 
Hazard statements 
Precautionary statements 
NONH for all modes of transport
WGK Germany 


Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Frequently Asked Questions

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If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
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What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
What is the solution stability of product I2760, (-)-Isoproterenol (+)-bitartrate salt?
Product I2760, (-)-Isoproterenol (+)-bitartrate salt, is soluble in water at 50 mg/ml. Solutions are sensitive to oxidation, discoloring quickly to brownish-pink. Preparation of fresh solutions using degassed water are recommended.
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