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I4161 Sigma-Aldrich

Interleukin-2 from mouse

IL-2, recombinant, expressed in E. coli, carrier free

Synonym: IL-2, T-cell growth factor, mIL-2

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Properties

Related Categories Cell Culture, Growth Factors and Cytokines, Interleukin-2, Interleukins (IL), Reagents and Supplements More...
Quality Level   200
biological source   mouse
recombinant   expressed in E. coli
assay   ≥97% (SDS-PAGE)
form   lyophilized powder
potency   ≤0.2 ng/mL ED50
quality   endotoxin tested
mol wt   17.2 kDa
packaging   pkg of 5X20 μg
  pkg of 20 μg
application(s)   cell culture | mammalian: suitable
impurities   ≤0.200ng/ml
color   white
UniProt accession no.   P04351
shipped in   dry ice
storage temp.   −20°C
Gene Information   mouse ... Il2(16183)

Description

Biochem/physiol Actions

Interleukin-2 (IL-2) is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. Recombinant human IL-2 is a 15.5 kDa protein, containing 134 amino acid residues including one intrachain disulfide bond.

Physical form

Lyophilized with no additives.

Reconstitution

Centrifuge vial prior to opening. Reconstitute the contents of the vial in water to a concentration range of 0.1-1.0 mg/mL.

IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant human IL-2 is a 15.5 kDa protein, containing 134 amino acid residues including one intrachain disulfide bond.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

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Peer-Reviewed Papers
15

References

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