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I5396 Sigma-Aldrich

Interleukin-1α from mouse

IL-1α, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Synonym: IL-1α, mIL-1α



Analysis Note

The biological activity is measured in a cel proliferation assay using the murine helper T cell line, D10.G4.1.

Biochem/physiol Actions

Interleukin-1 (IL-1), originally known as Lymphocyte Activating Factor (LA F), activates T cells and lymphocytes, which then proliferate and secrete Interleukin-2 (IL-2). The proliferative activity of human IL-1α is tested in culture using the murine cell line D10S.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.25 mg bovine serum albumin.

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 

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Cell Culture Guide
Protocols & Articles


Interleukin Family (IL)

The Interleukins comprise a disparate group of cytokines and growth factors that are produced by and released from leukocytes. Interleukin-1β (1L-1β) is released primarily from stimulated macrophages...
Jennifer Fries
BioFiles 2009, 4.5, 16.
Keywords: Anti-inflammatory agents, Antitumor agents, Cancer, Cell proliferation, Gene expression, Growth factors, Transcription

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