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  • I5781 - Immunobiology: The Immune System in Health and Disease, 5th ed.

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Immunobiology: The Immune System in Health and Disease, 5th ed.

  •  ISBN-10 0-8153-3642-X

  •  ISBN-13 978-0-8153-3642-6

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publication info   C.A. Janeway, et al., Garland Publishing, 2001, 752 pp., soft cover/CD-ROM

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General description

The fifth edition is a major reorganization in which innate immune mechanisms that form the front line of host defense against infection occupy a new chapter at the beginning. Chapters describing antigen-receptors of B and T lymphocytes and generation of diversity in their antigen-binding regions have been reorganized to emphasize unifying concepts that apply to both B and T cell receptors. There is a single chapter on lymphocyte development that extends its unified approach to B and T cell development to a consideration of the survival and maturation of lymphocytes in peripheral lymphoid tissues. Discussion of T cell and B cell effector functions have been kept separate. CD-ROM included.

Table of Contents

Part I AN INTRODUCTION TO IMMUNOBIOLOGY AND INNATE IMMUNITY
Chapter 1 Basic Concepts in Immunology
Chapter 2 Innate Immunity
Part II THE RECOGNITION OF ANTIGEN
Chapter 3 Antigen Recognition by B-cell and T-cell Receptors
Chapter 4 The Generation of Lymphocyte Antigen Receptors
Chapter 5 Antigen Presentation to T Lymphocytes
Part III THE DEVELOPMENT OF MATURE LYMPHOCYTE RECEPTOR REPERTOIRES
Chapter 6 Signaling Through Immune System Receptors
Chapter 7 The Development and Survival of Lymphocytes
Part IV THE ADAPTIVE IMMUNE RESPONSE
Chapter 8 T-Cell Mediated Immunity
Chapter 9 The Humoral Immune Response
Chapter 10 Adaptive Immunity to Infection
Part V THE IMMUNE SYSTEM IN HEALTH AND DISEASE
Chapter 11 Failures of Host Defense Mechanisms
Chapter 12 Allergy and Hypersensitivity
Chapter 13 Autoimmunity and Transplantation
Chapter 14 Manipulation of the Immune Responses
Afterword

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