• USA Home
  • I7904 - Indomethacin heptyl ester

EMAIL THIS PAGE TO A FRIEND
I7904 Sigma-Aldrich

Indomethacin heptyl ester

methyl acetate solution, ≥98% (HPLC)

Purchase

Properties

Related Categories A to C, Application Index, Arachidonic Acid Cascade, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules,
Quality Level   100
assay   ≥98% (HPLC)
form   methyl acetate solution
potency   0.04 μM IC50 (for human recombinat COX-2)
shipped in   wet ice
storage temp.   −20°C
SMILES string   CCCCCCCOC(=O)Cc1c(C)n(C(=O)c2ccc(Cl)cc2)c3ccc(OC)cc13
InChI   1S/C26H30ClNO4/c1-4-5-6-7-8-15-32-25(29)17-22-18(2)28(24-14-13-21(31-3)16-23(22)24)26(30)19-9-11-20(27)12-10-19/h9-14,16H,4-8,15,17H2,1-3H3
InChI key   PYBCHCVNKGZCOH-UHFFFAOYSA-N

Description

Packaging

5 mg in glass bottle

Application

Used to inhibit COX-1 and COX-2. To achieve 50% inhibition of human recombinant COX-2 use I7904 at 0.04 uM/mL .

Biochem/physiol Actions

Potent cyclooxygenase-2 inhibitor. 1700 times greater activity against COX-2 than COX-1.

Other Notes

Derivatized indomethacin.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Supplemental Hazard Statements 
Repeated exposure may cause skin dryness or cracking.
RIDADR 
UN1231 - class 3 - PG 2 - Methyl acetate, solution
WGK Germany 
3
Flash Point(F) 
8.6 °F
Flash Point(C) 
-13 °C

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Certificate of Origin (COO)

Please Enter a Lot Number
Protocols & Articles
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?