EMAIL THIS PAGE TO A FRIEND
I8280 Sigma-Aldrich

Indomethacin

meets USP testing specifications

Synonym: 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid

  • CAS Number 53-86-1

  • Empirical Formula (Hill Notation) C19H16ClNO4

  • Molecular Weight 357.79

  •  Beilstein/REAXYS Number 497341

  •  EC Number 200-186-5

  •  MDL number MFCD00057095

  •  PubChem Substance ID 24896136

Purchase

Properties

Related Categories Core Bioreagents, Enzyme Inhibitors, Research Essentials More...
InChI Key   CGIGDMFJXJATDK-UHFFFAOYSA-N
assay   98.0-101.0%
form   powder
suitability   meets USP testing specifications
Mode of action   enzyme | inhibits
Gene Information   human ... ALB(213), ALOX5(240), ELA2(1991), GPR44(11251), IL1A(3552), PLA2G1B(5319), PTGDR(5729), PTGS1(5742), PTGS2(5743)
mouse ... Alox5(11689), Ptgdr(19214), Ptger1(19216), Ptger2(19217), Ptger3(19218), Ptger4(19219), Ptgs1(19224), Ptgs2(19225)
rat ... Alox5(25290), Ptgs1(24693), Ptgs2(29527)

Description

Packaging

5, 25, 100 g in glass bottle

Biochem/physiol Actions

Cyclooxygenase (COX) inhibitor that is relatively selective for COX-1.

Used as a non-selective inhibitor of cyclooxygenases, COX1 and COX2, leading to reduced prostaglandin biosynthesis from arachidonic acid.

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGI
WGK Germany 
3
RTECS 
NL3500000

Documents

Certificate of Analysis

???PDP_SDS_LOT_NUMBER_ERROR_MSG???

Certificate of Origin

???PDP_SDS_LOT_NUMBER_ERROR_MSG???
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?