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  • J104 - Anti-c-Jun antibody produced in rabbit

J104 Sigma

Anti-c-Jun antibody produced in rabbit

affinity isolated antibody, lyophilized powder



Related Categories Alphabetical Index, Antibodies, Antibodies for Gene Regulation, Antibodies to Chromatin, Antibodies to Common Transcription Factors,
species reactivity   mouse
application(s)   western blot (chemiluminescent): 10 μg/mL using c-Jun expressed in serum stimulated mouse fibroblasts (NIH3T3)
clone   polyclonal
antibody form   affinity isolated antibody
form   lyophilized powder
storage temp.   −20°C
Gene Information   mouse ... Jun(16476)
biological source   rabbit
conjugate   unconjugated



synthetic peptide corresponding to amino acid residues 91-105 of mouse c-Jun.

Physical form

Lyophilized, purified rabbit IgG, containing 0.05% sodium azide.


Anti-c-Jun antibody produced in rabbit has been used as a primary antibody in immunohistochemistry.


Reconstitute with 100 μL deionized water.

Biochem/physiol Actions

The protooncogene c-Jun encodes a member of the jun family that forms a component of the transcription factor AP-1 (Activator Protein-1). It dimerizes with a member of the Fos family via the leucine-zipper motif to form AP-1, a factor involved in binding to TPA (12-O-tetradecanoylphorbol 13-acetate) response element (TRE) of various genes that include human collagenase, metallothionein IIa, stromelysin, interleukin 2, SV40 and polyoma. The dimers formed are involved in the activation of AP-1 dependent genes. AP-1 regulates the transcription of mammalian DDI (DNA-damage-inducible) genes.

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Certificate of Analysis

Certificate of Origin

Safety Information

Personal Protective Equipment  Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RIDADR  NONH for all modes of transport
WGK Germany  nwg
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Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

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