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J4330 Sigma-Aldrich

JTE-907

≥98% (HPLC)

Synonym: N-(1,3-benzodioxol-5-ylmethyl)-1,2-dihydro-7-methoxy-2-oxo-8-(pentyloxy)-3-Quinolinecarboxamide

  • CAS Number 282089-49-0

  • Empirical Formula (Hill Notation) C24H26N2O6

  • Molecular Weight 438.47

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, J
assay   ≥98% (HPLC)
color   white to off-white
solubility   DMSO: ≥10 mg/mL
storage temp.   2-8°C

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

JTE-907 is a cannabinoid CB2 ligand (inverse agonist). CB2 cannabanoid receptors are expressed in periferal nerves and other non CNS tissues, but are not expressed in the brain. CB2 is believed to have a role in nociceptive pain, but additional functions pertaining to the immune system have yet to be determined. CB2 selective agonists and antagonists provide a necessary tool for functional analyses.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
VB1150900

Documents

Certificate of Analysis

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Making Headway

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Protocols & Articles

Articles

Cannabinoid Receptors

Cannabinoid receptors derive their name from Δ9-tetrahydrocannabinol (Δ9-THC), the psychoactive principle in Cannabis sativa (marijuana). Although marijuana has been in use for over 4,000 years as a ...
Keywords: AGE, Atomic absorption spectroscopy, Endocannabinoids, Gene expression, Infrared spectroscopy, Ligands, Metabolism, Neurotransmitters, Transduction

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