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K1639 Sigma-Aldrich

K-252a

from Nonomuraea longicatena, ≥98% (HPLC)

  • CAS Number 99533-80-9

  • Empirical Formula (Hill Notation) C27H21N3O5

  • Molecular Weight 467.47

  •  MDL number MFCD00161522

  •  PubChem Substance ID 24896210

  •  NACRES NA.77

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Properties

Related Categories Antibiotics, Antibiotics A to Z, Antibiotics G-M, Antibiotics by Application, Antineoplastic and Immunosuppressive Antibiotics,
Quality Level   200
biological source   Nonomuraea longicatena
assay   ≥98% (HPLC)
solubility   DMF: 1 mg/mL
  DMSO: 1 mg/mL
Mode of action   enzyme | inhibits
antibiotic activity spectrum   viruses
shipped in   dry ice
storage temp.   −20°C
SMILES string   [H][C@]12C[C@](O)(C(=O)OC)[C@](C)(O1)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35
InChI   1S/C27H21N3O5/c1-26-27(33,25(32)34-2)11-18(35-26)29-16-9-5-3-7-13(16)20-21-15(12-28-24(21)31)19-14-8-4-6-10-17(14)30(26)23(19)22(20)29/h3-10,18,33H,11-12H2,1-2H3,(H,28,31)/t18-,26+,27+/m1/s1
InChI key   KOZFSFOOLUUIGY-SOLYNIJKSA-N
Gene Information   human ... NTRK1(4914)
rat ... Prkca(24680)
Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
NZ0550000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles

Articles

EGF Signaling: Tracing Cancer's Path

The epidermal growth factor (EGF) family is a group of structurally related proteins that regulate cell proliferation, migration and differentiation via tyrosine kinase receptors on target cells. The...
Keywords: Apoptosis, Cancer, Cell proliferation, Cloning, Gene expression, Growth factors, Ligands, Morphogenesis, Phosphorylations, Transcription, Transduction, transformation

Peer-Reviewed Papers
15

References

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Description

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05288 K-252a, from Nocardiopsis sp.
K2015 K-252a, Ready Made Solution, from Nonomuraea longicatena, >98%

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