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  • K4889 - Anti-Potassium Channel KVβ2 antibody produced in rabbit

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K4889 Sigma-Aldrich

Anti-Potassium Channel KVβ2 antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Synonym: Anti-KCNAB2

  •  NACRES NA.41

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Properties

Related Categories Alphabetical Index, Antibodies, POD-POZ, Primary Antibodies
conjugate   unconjugated
clone   polyclonal
biological source   rabbit
application(s)   immunohistochemistry: suitable using mouse brain sections
  western blot: 1:200-1:400 using rat brain and Jurkat cells
species reactivity   mouse, human, rat
form   lyophilized powder
shipped in   dry ice
storage temp.   −20°C
antibody form   affinity isolated antibody
Quality Level   200
antibody product type   primary antibodies
UniProt accession no.   Q13303
Gene Information   human ... KCNAB2(8514)
mouse ... Kcnab2(16498)
rat ... Kcnab2(29738)

Description

Immunogen

synthetic peptide SPGMIYSTRYGSPKR(C), corresponding to amino acid residues 20-34 of rat KVβ2.

Target description

KVβ2, as well as the other KVβ subunits can bind to all the members of the large KV1.x (Shaker) channel subfamily. However, recent evidence suggests that it can also bind to members of the KV4.x subfamily. KVβ2 is the most abundant β subunit in the brain where it couples with all the KV1.x subunits, but the protein is also expressed in peripheral tissues including heart, lung and cells of hematopoietic origin such as T cells where it couples with KV1.3, the dominant voltage-dependent K+ channel in these cells.

Physical form

Lyophilized powder from phosphate buffered saline (PBS), pH 7.4, containing 1% BSA and 0.25% sodium azide.

Reconstitution

Reconstitute the lyophilized vial with 50μL or 200 μL deionized water, depending on package size. Further dilutions should be made using a carrier protein such as BSA (1-3%).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
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Protocols

Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detection methods, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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