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L0879 Sigma-Aldrich

Leu-Leu-Leu

≥90% (elemental analysis)

  • CAS Number 10329-75-6

  • Empirical Formula (Hill Notation) C18H35N3O4

  • Molecular Weight 357.49

  •  MDL number MFCD00038309

  •  PubChem Substance ID 24896267

  •  NACRES NA.26

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Properties

Related Categories Biochemicals and Reagents, Dipeptides and Tripeptides, Peptides, Tripeptides
Quality Level   200
assay   ≥90% (elemental analysis)
form   powder
application(s)   electron microscopy: suitable
  mass spectrometry (MS): suitable
color   white
storage temp.   −20°C
SMILES string   CC(C)CC(N)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(O)=O
InChI   1S/C18H35N3O4/c1-10(2)7-13(19)16(22)20-14(8-11(3)4)17(23)21-15(18(24)25)9-12(5)6/h10-15H,7-9,19H2,1-6H3,(H,20,22)(H,21,23)(H,24,25)
InChI key   DNDWZFHLZVYOGF-UHFFFAOYSA-N

Description

Amino Acid Sequence

Leu-Leu-Leu

Application

Trileucine (Leu-Leu-Leu), an endosome escape moiety, may be used for pH-dependent endosomal membrane disruption to release agents such as antisense oligonucleotides (AONs) inside cells. Trileucine is used to evaluate the absorption characteristics of reversed phase liquid chromatography (HPLC) media.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

TLC Analysis of Tripeptides on HPTLC Silica Gel 60 RP-18 F254s (analyte set 2)

From our library of Articles, Sigma-Aldrich presents TLC Analysis of Tripeptides on HPTLC Silica Gel 60 RP-18 F254s (analyte set 2)
Keywords: Chromatography, Thin layer chromatography

Peer-Reviewed Papers
15

References

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