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L0915 Sigma-Aldrich

Leukemia Inhibitory Factor soluble Receptor α human

>97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture

Synonym: LIFsRα

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, Hematopoietic Cytokines,
biological source   human
recombinant   expressed in baculovirus infected Sf21 cells
assay   >97% (SDS-PAGE)
form   lyophilized powder
potency   3-6 μg/mL ED50
mol wt   glycosylated form 100-110 kDa by SDS-PAGE
  predicted mol wt ~89 kDa
storage condition   avoid repeated freeze/thaw cycles
application(s)   cell culture | mammalian: suitable
impurities   endotoxin, tested
UniProt accession no.   P42702
storage temp.   −20°C
Gene Information   human ... LIFR(3977)

Description

Biochem/physiol Actions

Soluble LIF receptor α, a member of the cytokine receptor family, binds LIF and is antagonistic.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 2.5 mg bovine serum albumin.

Analysis Note

The biological activity is measured by its ability to inhibit the LIF dependent proliferation of TF-1 cells.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
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