L1012 Sigma-Aldrich

Linoleic acid

liquid, BioReagent, suitable for cell culture

Synonym: 9-cis,12-cis-Linoleic acid, cis-9,cis-12-Octadecadienoic acid, Telfairic acid

  • CAS Number 60-33-3

  • Linear Formula CH3(CH2)4CH=CHCH2CH=CH(CH2)7CO2H

  • Molecular Weight 280.45

  •  Beilstein Registry Number 1727101

  •  EC Number 200-470-9

  •  MDL number MFCD00064241

  •  eCl@ss 32190102

  •  PubChem Substance ID 24896270



Related Categories Biochemicals and Reagents, Cell Biology, Cell Culture, Fatty Acids and conjugates, Fatty Acyls,
product line   BioReagent
assay   ≥99%
form   liquid
refractive index   n20/D 1.466(lit.)
bp   229-230 °C/16 mmHg(lit.)
mp   −5 °C (lit.)
solubility   NaOH: 1 M
  ethanol: soluble
density   0.902 g/mL at 25 °C(lit.)
suitability   suitable for cell culture
storage temp.   −20°C
Gene Information   human ... SOAT1(6646), SOAT2(8435)



Fatty acid that is typically bound to a carrier molecule such as BSA or cyclodextrin for use in cell culture.


1, 5 g in ampule

100 mg in ampule

Sealed ampule.

Biochem/physiol Actions

Linoleic acid increases cell proliferation and gene expression of PPARα and its target genes such as acyl-CoA oxidase in primary duck hepatocytes .

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
Flash Point(F) 
>235.4 °F
Flash Point(C) 
>113 °C

Cell Culture Guide

Webinar - Hydrogels
Protocols & Articles


Lipid Induced Insulin Resistance

Obesity is a well-established risk factor for the development of insulin resistance. Obesity is associated with the increased deposition of lipids in non-adipose tissue with subsequent decreases in i...
Linda Stephenson, Ph.D.
Biofiles v6 n4, 9
Keywords: Angiogenesis, Antivirals, Apoptosis, Biological processes, Cardiovascular, Catalog, Catalysis, Cell culture, Cell proliferation, Deposition, Diabetes, Events, Gene expression, Growth factors, Hormones, Inflammation, Metabolism, Metabolites, Obesity, Phosphorylations, Physiological Processes, Reductions, Transcription, Transduction, Type

Omega-3 Fatty Acids and Heart Disease

The potential for the prevention and treatment of cardiovascular disease through increased dietary intake of omega-3 (w-3) fish oils is not a recent scientific discovery. A historically important stu...
BioFiles 2007, 2.2, 14.
Keywords: Anti-inflammatory agents, Biochemistry, Cardiovascular, Clinical, Degradations, Esterifications, Immunology, Inflammation, Lipid Metabolism, Metabolism, Metabolites, Methods, Nutrition, Oxidations, Transcription

Related Content

Cell Culture Troubleshooting Guide

Cell culture has become one of the most fundamental techniques for modeling biological systems, and is of increasing importance in the biotechnology and pharmaceutical sectors as well as an essential...
Keywords: Antibiotics, Apoptosis, Cell attachment, Cell culture, Cryopreservation, Filtration, Growth factors, Pharmaceutical, Phase transitions

Peer-Reviewed Papers


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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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