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L1040 Sigma-Aldrich

Livin β/ML-IAP human

>95% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous solution

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Properties

Related Categories Apoptosis Supressor Proteins and Antibodies, Apoptosis and Cell Cycle, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology,
Quality Level   200
recombinant   expressed in E. coli
assay   >95% (SDS-PAGE)
form   buffered aqueous solution
mol wt   32 kDa by SDS-PAGE
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... BIRC7(79444)

Description

Biochem/physiol Actions

Livin β/ML-IAP, a member of the inhibitor of apoptosis (IAP) protein family, inhibits the activation of caspase 9 in cell extracts incubated with cytochrome c and dATP.

Physical form

Solution in 25 mM Hepes, pH 7.5, 0.1 M sodium chloride, and 1 mM dithiothreitol.

Analysis Note

Biological activity is measured by its ability to inhibit DEVD-afc cleavage in cell extracts activated by cytochrome c and dATP.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles
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