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L1567 Sigma-Aldrich

Lipoprotein, high density from human plasma

lyophilized powder

Synonym: α-Lipoprotein, HDL, High density lipoprotein

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Properties

Related Categories Biochemicals and Reagents, Lipoproteins, Plasma & Blood Proteins, Plasma, Blood, and Related Proteins and Reagents, Proteins and Derivatives More...
Quality Level   200
biological source   human plasma
assay   ≥95% (agarose gel electrophoresis)
form   lyophilized powder
packaging   vial of ~10 mg protein (modified Lowry)
solubility   0.85% sodium chloride: soluble 10 mg/mL
storage temp.   2-8°C
Gene Information   human ... APOA1(335), APOA4(337), APOA5(116519), APOB(338), APOC1(341), APOC3(345), APOE(348)

Description

Biochem/physiol Actions

Lipids are transported in blood plasma among the various tissues by water-soluble complexes called lipoproteins, which differ in size as well as in their composition of lipids and proteins. Each lipoprotein complex contains a distinct number of apolipoproteins and lipid.

Physical form

Lyophilized from a solution of 0.15 M NaCl and 0.01% EDTA, pH 7.4

Other Notes

View more information on lipoprotein function and lipid transport at www.sigma-aldrich.com/enzymeexplorer.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Cholesterol Transport

Since cholesterol is a water-insoluble molecule it must be packaged for transport within the plasma. The particles that package cholesterol, cholesteryl esters, and triglycerides for transport, are c...
BioFiles 2007, 2.7, 13.
Keywords: Esterifications, Ligands

Omega-3 Fatty Acids and Heart Disease

The potential for the prevention and treatment of cardiovascular disease through increased dietary intake of omega-3 (w-3) fish oils is not a recent scientific discovery. A historically important stu...
BioFiles 2007, 2.2, 14.
Keywords: Anti-inflammatory agents, Biochemistry, Cardiovascular, Clinical, Degradations, Esterifications, Immunology, Inflammation, Lipid Metabolism, Metabolism, Metabolites, Methods, Nutrition, Oxidations, Transcription

Plasma Derived Proteins and Enzymes

Despite their complexity, blood and plasma are abundant biological resources for the discovery of drug targets and biomarkers for human disease. It is estimated that plasma may contain as many as 40,...
BioFiles 2006, 1.5, 2.
Keywords: Applications, Gas chromatography, Type

Peer-Reviewed Papers
15

References

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